Transcription Factor Phosphorylation by pp90

Transcription factor phosphorylation by the DNA-dependent protein kinase.

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Induction of Heme Oxygenase -1 By Lipocalin 2 Mediated By Nf-Kb Transcription Factor

Purpose: Effect of lipocalin 2 on the expression of heme oxygenase I , II and NF-kB transcription factor was the purpose of this survey. Materials and Methods: Lcn2 was cloned to pcDNA3.1 plasmid by using genetic engineering method. The recombinant vector was transfected to CHO and HEK293T to establish stable cell expressing lipocalin 2. The presence of lipocalin 2 gene in these cells was confi...

Phosphorylation-Dependent SUMOylation of the Transcription Factor NF-E2

Nuclear factor erythroid-derived 2 (NF-E2), a heterodimer composed of p45 and p18, is a transcriptional activator in hematopoietic progenitors. The transcriptional activity of NF-E2 is not only upregulated by SUMOylation but also stimulated by the cAMP-dependent protein kinase A (PKA). However, the relationship between SUMOylation and phosphorylation in the activation of NF-E2 is unclear. In th...

Persistent ERK Phosphorylation Negatively Regulates CREB Activity via Recruitment of CBP to pp90

Improving Rice (Oryza sativa L.) Drought Tolerance by Suppressing a NF-YA Transcription Factor

The response to drought stress is a complicated process involving stress sensing, intracellular signaltransduction, and the execution of a cellular response. Transcription factors play important roles in the signaling pathways including abiotic stress. In the present study a rice NF-YA transcription factor gene was partially characterized following dehydration. Disrupting the gene via a T...